PKRRATING FUNDAMENTALS EXPLAINED

A) Alignment in the a few distinctive protomers existing in the asymmetric device of the AMPPNP complicated of the unphosphorylated PKR kinase domain Together with the AMPPNP complicated of a phosphorylated PKR kinase domain (PDB 2A19, chain B). The color plan is indicated within the legend. B) Comparison in the Energetic sites. For clarity, only c